Most detoxification in the human body takes place in two phases: Phase 1 (oxidation), and Phase 2 (conjugation). During detoxification in the body, enzymes attach chemical groups to the toxins during phase 1, making them more reactive. Phase 2 facilitates the binding or conjugating of these substances to compounds that can shuttle the toxins out of the cells and ultimately out of the body. Suforaphane, the sulfur chemical found in broccoli seeds, has been shown to be a potent stimulator of phase 2 enzymes in the human body. N-acetyl cysteine is a precursor of the antioxidant glutathione which is commonly used to conjugate numerous toxins in phase 2 detoxification.
So in essence, Phase 1 puts a handle on the toxins, and Phase 2 grabs them and pulls them out of the body. Chemicals found in things like plastics, air pollution, cigarette smoke, and pesticides will stimulate Phase 1 detoxification, but not Phase 2. Without compounds like sulfur from cruciferous vegetables and sulfur-containing amino acids like N-Acetyl Cysteine, toxins that have gone through Phase 1 are actually more dangerous and can damage tissues in the body, leading to more disease. (US Orders Only; Thorne Does Not Ship to Canada)
In 1992, Johns Hopkins researchers discovered that a compound in broccoli called sulforaphane can act as a potent promoter of antioxidant and detoxification protein production in human cells.* Over the last decade, studies have demonstrated a reduced risk for cancer, a higher level of cellular antioxidants, and an increase in toxin excretion with the consumption of sulforaphane compounds.* Crucera-SGS comes from the same team at Johns Hopkins and is a proprietary extract from hybrid broccoli seeds that contain research verified potency of the active sulforaphane glucosinolate (SGS) compounds.*
The body uses glutathione as its primary antioxidant found in each and every cell.* Glutathione is also utilized in phase 2 detoxification to bind to toxins and shuttle them out of the cells and ultimately the body.*N-acetyl cysteine (NAC), the amino acid found in Cysteplus, is a foundational ingredient for supporting optimal levels of the human body’s most important antioxidant, glutathione.* NAC is the precursor for L cysteine which is the rate-limiting ingredient for the body to make glutathione.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.